|
KMID : 0358320120530050297
|
|
Korean Journal of Urology
2012 Volume.53 No. 5 p.297 ~ p.303
|
|
|
High-Grade Prostatic Intraepithelial Neoplasia
|
|
Klink Joseph C
Miocinovic Ranko
Galluzzi Cristina Magi
Klein Eric A
|
|
|
Abstract
|
|
|
|
High-grade prostatic intraepithelial neoplasia (HGPIN) has been established as a precursor to prostatic adenocarcinoma. HGPIN shares many morphological, genetic, and molecular signatures with prostate cancer. Its predictive value for the development of future adenocarcinoma during the prostate-specific antigen screening era has decreased, mostly owing to the increase in prostate biopsy cores. Nevertheless, a literature review supports that large-volume HGPIN and multiple cores of involvement at the initial biopsy should prompt a repeat biopsy of the prostate within 1 year. No treatment is recommended for HGPIN to slow its progression to cancer.
|
|
|
KEYWORD
|
|
|
HGPIN, High grade prostatic intraepithelial neoplasia, Prostate biopsy, Prostate cancer
|
|
|
FullTexts / Linksout information
|
|
  
|
|
|
Listed journal information
|
|
  
|